Survival time and side effects associated with treatment of granulomatous menigencephalomyelitis in dogs: a systematic review
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Keywords

inflammatory diseases, central nervous system, prednisone.

Abstract

Granulomatous meningoencephalomyelitis (MEG) is an inflammatory disease of the central nervous system (CNS) of dogs and its origin is still unknown. MEG is classified as disseminated, focal and ocular. In the first, the prognosis is unfavorable and the survival time is inferior to the other forms. The definitive diagnosis is obtained by histopathological analysis of CNS biopsy or post mortem examination. Glucocorticoids are the basis of treatment, but their side effects are a limiting factor. Over the years the authors have sought to find a drug that can be used in conjunction with corticosteroid therapy to reduce its dose and side effects. The aim of this systematic literature review was to evaluate the best MEG treatment protocol for longer survival and fewer side effects.

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